ATG4B anticorps

N° du produit ABIN1732017

Cet anticorps anti-ATG4B est un anticorps Lapin Polyclonal détectant ATG4B dans WB et IHC (p). Adapté pour Humain, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis et Mammifères.

Aperçu rapide pour ATG4B anticorps (ABIN1732017)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis, Mammifères

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ATG4B anticorps

Specificité: Reacts with human ATG4B

Réactivité croisée: Souris, Poisson Zèbre, Poulet, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with chicken, xenopus, mouse, pufferfish, rat and zebrafish protein.

Purification: Purified (protein G)

Immunogène: Synthetic peptide from human ATG4B.

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 μg/mL), WB (1 - 3 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS, 0.2 % gelatin, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.

ID gène: 23192

Pathways: Autophagy